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[nukkad] cure for diabetes



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http://us.rediff.com/news/2004/jan/07diab.htm 

Indian scientists claim cure for diabetes 

January 07, 2004 12:12 IST 

Indian scientists claimed to have developed a drug as 
a 'cure' to diabetes from a plant found in West 
Bengal's Purulia hills. 

"The drug - 'ICB201' -- has been derived from a plant 
after it was noticed that people in Purulia hills used 
it in case of diabetic problems," Dr S Bhattacharya of 
Indian Institute of Chemical Biology, Kolkata, said. 

Bhattacharya was delivering the B C Guha Memorial 
Award Lecture on 'Confronting Diabetic Type II: A 
global Epidemic' in Kolkata on Tuesday. 

Asserting that earlier there was 'practically no drug 
to treat the Type II diabetes', he said, "'ICB201' 
acts by lowering the fatty acid levels in blood. 
Higher levels of fatty acids in blood diminish 
activity of insulin which causes diabetes." 

The Phase I toxicity studies on mice have been carried 
out and the data would be submitted to concerned 
authorities. Phase II studies would start in about 
two-three months and the drug is likely to hit the 
market in next two to three years, Bhattacharya said. 

Pointing out that patents were being filed for the 
'invention', he said work on the medicine started four 
years back. However, he refused to reveal the name of 
the plant. 

Bhattacharya said, "It is now being realised that more 
than glucose, it is the levels of fatty acids which 
play more important role in diabetes. The disease was 
being found even in thin people. In fact it was shown 
in animals that if fat is removed, diabetes manifests 
and if fat is replaced, diabetes disappears." 

It happens because fat cells take fatty acids from 
circulation thus lowering their levels, he said. 

"While in Type I, there is deficiency of insulin, Type 
II is independent of insulin. However, in both the 
types, levels of glucose rise in the blood," he said. 

In Type II diabetes, the insulin, though present, is 
unable to act, thereby leading to enhanced glucose 
levels, he said. "Currently both the disease types are 
treated by giving insulin to the patients which 
actually can do harm." 


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have a great day !
- pravin walunjkar. 
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